Productos

HBV Adefovir-resistant Mutants Real Time PCR Kit
10 de septiembre de 2015
HBV Genotype B,C&D Real Time PCR Kit
10 de septiembre de 2015
Show all

HBV Genotype B&C Real Time PCR Kit


HD-0006

Categorías: , , , , .
   
Descripción

1. Intended Use
HBV genotype B&C real-time PCR kit is used for the detection of HBV genotype B&C in serum or
plasma by using real time PCR systems.

2. Product Description
Hepatitis B virus (HBV) is one of the most common infectious diseases in the world. More than 300
million people worldwide are estimated to have chronic HBV infection. Ten percent of these patients
will die as a direct consequence of persistent viral infection. At present, seven genotypes of hepatitis B
virus (HBV) have been recognized (A–G). Previous studies have indicated a geographic distribution of
HBV genotype; for example, genotypes A and D are prevalent in Western countries, while B and C are
more frequent in Asia. In Asia, HBV genotype C (HBV/C) induces more aggressive liver disease
associated with the development of cirrhosis and hepatocellular carcinoma (HCC) than HBV/B and
has a lower response rate to interferon therapy compared to HBV/B. Furthermore, HBV/A is
associated more frequently with chronic infection than HBV/D in Europe. Patients infected with
HBV/B in Taiwan develop HCC at a much earlier age than those with HBV/C, while young adult
Japanese patients (≤30 years) infected with HBV/B do not develop HCC.
HBV genotype B&C real-time PCR kit contains a specific ready-to-use system for the detection of the
HBV genotype B and HBV genotype C in one reaction using PCR (polymerase chain reaction) in the
real-time PCR system. The master contains reagents and enzymes for the specific amplification of the
HBV genotype B and HBV genotype C DNA fragment. Fluorescence is emitted and measured by the
real time systems´ optical unit during the PCR. The detection of amplified HBV genotype B DNA
fragment is performed in fluorimeter channel HEX/VIC/HEX with the fluorescent quencher BHQ1.
Detection of amplified DNA fragment of HBV genotype C is performed in fluorimeter channel FAM
with the fluorescent quencher BHQ1. DNA extraction buffer is available in the kit. In addition, an
external HBV genotype B positive control and HBV genotype C positive control are supplied in the
kit.

Comentarios (0)

Reseñas

No hay reseñas todavía.

Sé el primero en opinar “HBV Genotype B&C Real Time PCR Kit”


*